Alpha Delta Pi has been involved in philanthropic work since its inception, at the 1979 Grand Convention, the convention body voted to adopt the Ronald McDonald Houses (Children's Oncology Services, Inc.) as the new national philanthropy. Ronald McDonald Houses are located throughout the world near hospitals, and serve young cancer patients and their families as a "home away from home" during their treatment and convalescence. Collegiate and alumni members of Alpha Delta Pi volunteer to work at the Ronald McDonald Houses, and to sponsor fundraising events for the houses. In 1987, Alpha Delta Pi was recognized by the Children's Oncology Services, Inc. for having contributed over $2 million to Ronald McDonald Houses. Fundraising for this philanthropy is overseen by the Alpha Delta Pi Foundation, Inc.

The Ronald McDonald House in Johnson City, Tn.