Edwards Lab

 
 

Our research is based upon gaining a greater understanding of the physiological processes associated with the maintenance of acid/base and osmoregulatory homeostasis in fishes: Specifically the role epithelial transport proteins and environmental salinity. We use an integrative approach to our research combining systemic physiology with biochemistry and molecular biology to answer fundamental research questions. A large portion of our research is undertaken during the summer months at the Mount Desert Island Biological Laboratory, Salisbury Cove, Maine.

 

Research Interests

Current Research Projects

Current Lab Members: Graduate Students: Richard de Triquet (L) and Salvatore Blair (R)

Osmoregulation in the sea lamprey Petromyzon marinus.


Identification and regulation of Rh glycoproteins in Agnathan fishes and their role nitrogenous waste excretion


The role of the sodium proton exchangers (NHEs) in the ability of fishes to maintain acid/base balance.


My Research Philosophy: I want to encourage students to be free to follow their research passion in a supportive environment. I strongly encourage students to pursue opportunities for study and travel abroad through collaborative research associations and participation at both national and international conferences.


Students interested in pursuing MSc research projects within the Edward’s lab should contact me directly at edwardssl@appstate.edu


Interested students should provide a list of research interests along with a statement of educational background and undergraduate GPA and GRE scores if available.

Department of Biology,

Appalachian State University

PO Box 32027

Boone, NC, 28608-2027


Email: edwardssl@appstate.edu


Office Phone: +1 828 262 2679

Selected Publications

1.Claiborne, J. B., Choe, K. P., Evans, D. H., Freiji, A., Havird, J., Morrison-Shetlar, A. I., Weakley, J. C. and Edwards, S. L. (2008). Molecular detection and immunological localization of gill Na+/H+ exchange (NHE2) in the dogfish (Squalus acanthias). Am. J. Physiol. Reg Inter. Physiol. 294: 1092-1102. pdf

2.Choe,K.P. Edwards, S.L. Claiborne, J.B. Evans, D.H. (2007) The putative mechanism of Na+ absorption in euryhaline elasmobranchs exists in the gills of a stenohaline marine elasmobranch, Squalus acanthias J. Comp. Biochem. Physiol. Part A. 146:155-162.

  1. 3.Catches J.S, Burns, J.M. Edwards, S.L., Claiborne, J.B. (2006) Na+/H+ antiporter (NHE2), V-type H+ATPase and Na+/K+-ATPase immunolocalization in a marine teleost (Myoxocephalus octodecimspinosus). J.Exp. Biol., 209: 3440-3447.

  2. 4.Edwards, S.L., Wall, B.P., Morrison-Shetlar, A.I., Sligh, S, Weakley, J.C. and Claiborne, J.B. (2005). The effect of environmental hypercapnia and salinity on the expression of NHE-like isoforms in the gills of a euryhaline fish (Fundulus heteroclitus). J. Exp. Zool., 303A 464-475.

  3. 5.Choe, K.P, O’Brien, S, Evans, D.H., Toop, T, Edwards, S.L. (2004) Immunolocalisation of Na+/K+-ATPase, carbonic anhydrase II and vacuolar H+-ATPase in the gills of freshwater adult lamprey Geotria australis. J. Exp. Zool., 301A: 654-66